名字:张霞
照片:
![](/__local/5/2C/7A/7897D406342B367485B2BB9103F_7F31482D_3DDD.jpg)
职称:讲师
招生专业:医学检验技术、免疫学
联系电话:17608407389
电子邮箱:zx717@hunnu.edu.cn
通讯地址:湖南省长沙市岳麓区桐梓坡路371号,吕氏贵宾会0022,邮编:410013
简介:
张霞,医学博士,2006年获得山东大学临床医学学士学位,2011年获得山东大学免疫学博士学位。后在青岛吕氏贵宾会0022附属烟台毓璜顶医院检验中心工作5年,主要从事血液病的辅助诊断。2016年进入吕氏贵宾会0022免疫教研室工作。 主要从事肿瘤、炎症性疾病领域的研究。
主持的科研项目:
(1)国家自然科学基金青年项目,PDCD4抑制细胞自噬对卵巢癌恶性行为的影响及分子机制,81202069,2013.1-2015.12,23万元
(2)湖南省自然科学基金青年项目, 2018JJ3365, PDCD4在肿瘤相关成纤维细胞促进卵巢癌上皮间质化中的作用及机制研究, 2018/01 -2020/12, 5万元
(3)湖南省教育厅重点项目, 20A308,程序性细胞死亡4对急性B淋巴细胞白血病的抑制作用研究, 2021/01-2023/12, 6万元
(4)湖南省卫生健康委一般资助项目, 202102071747,抑癌基因PDCD4对慢性粒细胞白血病的作用研究, 2021/01-2023/12, 4万元
代表性学术论文:
1.Liang Huang, Anqi Zhang, Chunyan Tang, Jinmei Wei, Miao Li, Shishan Yuan, Huihui Zhang, Xia Zhang*. Identification of potential prognostic markers for lung adenocarcinoma using comprehensive analysis. Mol Med Rep. 2023 Aug;28(2):149.
2.龙馨妍;何泽诏;彭鹏;李涛;张慧慧;袁仕善;张霞* ;程序性细胞死亡蛋白4调控K562细胞活力和 凋亡的研究,中国病理生理杂志, 2021, 37(7): 1210-1218。
3.彭鹏;张安琪;周曼莉;刘霏柳;张慧慧;张霞*; USP1通过调控E2F1对膀胱癌细胞增殖和周期的作用研究。中国细胞生物学学报。2022, 44(12): 2267–2275。
4.XIA ZHANG, XIAOLU ZHANG, LILI ZHUANG, CANGCANG XU, TAO LI, GUILI ZHANG and YING LIU. Decreased regulatory T.cell frequency and interleukin.35 levels in patients with rheumatoid arthritis. EXPERIMENTAL AND THERAPEUTIC MEDICINE 16: 5366-5372, 2018
5.Zhang, Xia,Liu, Riming,Huang, Baohua,Zhang, Xiaolu,Yu, Weijuan,Bao, Cuixia,Li, Jie,Sun, Chengming. Programmed cell death 4 and BCR-ABL fusion gene expression are negatively correlated in chronic myeloid leukemia,Oncology Letters,2016,12(4):2976~2981
6.Huang, Baohua,Chen, Lei,Bao, Cuixia,Sun, Chengming,Li, Jie,Wang, Lipeng,Zhang, Xia*. The expression status and prognostic significance of programmed cell death 1 ligand 1 in gastrointestinal tract cancer: a systematic review and meta-analysis.,OncoTargets and Therapy,2015,8:2617~2625
7.Zhang Xia,Wang, Xiaoyan,Song, Xingguo,Wei, Zengtao,Zhou, Chengjun,Zhu, Faliang,Wang, Qun,Ma, Chunhong,Zhang, Liling. Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas,ONCOLOGY REPORTS,2011,25(2):353~358
8.Zhang, Xia,Wang, Xiaoyan,Song, Xingguo,Liu, Chunmei,Shi, Yongyu,Wang, Yukun,Afonja, Olubunmi,Ma, Chunhong,Chen, Youhai H,Zhang, Lining. Programmed cell death 4 enhances chemosensitivity of ovarian cancer cells by activating death receptor pathway in vitro and in vivo,Cancer Science,2010,101(10):2163~2170
9.Song, Xingguo,Zhang, Xia,Wang, Xiaoyan,Zhu, Faliang,Guo, Chun,Wang, Qun,Shi, Yongyu,Wang, Jianing,Chen, Youhai,Zhang, Lining,Tumor expression of autophagy-related gene ATG5.,Autophagy,2013,9(5):743~755
10.Ding, Lingling,Zhang, Xia,Zhao, Miaoqing,Qu, Zhonghua,Huang, Shanying,Dong, Mei,Gao, Fei. An essential role of PDCD4 in progression and malignant proliferation of gastrointestinal stroma tumors. Med Oncol,2012,29(3):1758~1764
11.Li, Haiyan,Zhang, Xia, Song, Xingguo,Zhu, Faliang,Wang, Qun,Guo, Chun,Liu, Chunmei,Shi, Yongyu,Ma, Chunhong,Wang, Xiaoyan,Zhang, Lining. PDCD5 promotes cisplatin-induced apoptosis of glioma cells via activating mitochondrial apoptotic pathway,Cancer Biology and Therapy,2012,13(9):822~830